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Careers in Rare Diseases Clinical Research

In rare disease, every single patient is precious. Our team understands the complex patient and disease profiles that drive challenging clinical development plans. Discover where your skills can strive to create life-changing achievements for every person involved. Through our "With Heart" approach, we are dedicated to making a remarkable impact on rare disease patients. Together, let's make a difference in rare disease research and patient lives.

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Experience in the past 5 years with rare diseases

  • 490+clinical projects

  • 85,000+patients

  • 17,500+sites

Our industry leadership

Over 400 million people globally suffer from a rare disease – that’s more than cancer and AIDS combined! Yet only ~5% rare diseases have an approved treatment. In the past five years, our rare disease team has worked on over 490 clinical projects. Parexel’s integrated patient-first approach ensures intentional design to meet the needs of rare disease patients, caregivers and sponsors through industry-leading medical, scientific, and regulatory expertise and innovation.

Cristina, an Italian American woman and a Clinical Operations Manager at Parexel, working from home.

Your expertise, your difference for patients

Your expertise will make trials possible, by embarking on a new era of rare disease and pediatric drug development, like precision medicine concepts, protecting the endpoints, and embedding patient insights.

Your work will make the trial process easier for the patients and families by focusing on their needs. Rare disease requires out-the-box, creative thinking – BE THE CHANGE!

Our Employee Insights

We’re a dedicated group of individuals who are passionate about the science, and helping patients with academic, regulatory, and industry backgrounds, as well as direct clinical experience. We work together to design, optimize, and streamline trails for patients and sponsors alike.

Rachel, a female white English, with long straight ash blond hair, and a closed smile, looking at the camera.

Rachel

Executive Director, Rare Disease, Center of Excellence

I have been working in the rare and ultra-rare disease field for over a decade, starting our at a pharmaceutical company before moving into the world of CROs where I have the opportunity to impact so many different indications, geographies and most importantly – patients. It was the parents and caregivers in the early days of my career in pediatric epilepsy and gene therapy trials that ignited my passion for working in this challenging space, along with the ever-changing environment and the fact that every program is different; allowing me to really lean into my empathy, creativity and knowledge every day. This is highlighted in the work I am doing at Parexel with N-Lorem, a non-profit foundation providing personalised antisense oligonucleotide (ASO) treatments to nano-rare patients who have and will never have any other treatment option. The first child dosed is now standing independently and can walk after being immobile. We did that!

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Elizabeth, a female white American, long brown hair with big waves, smiling at the camera.

Elizabeth

SVP, Clinical Operations

I work With Heart™ because of the work I did in cystic fibrosis. As a program lead for a small biotech pharmaceutical company, we had a drug that looked promising as a disease modifier for this rare disease with unmet needs. At scientific conferences, parents of children with cystic fibrosis would approach me and ask me to work harder and be better. At night, after the conference days, I could hear the constant coughing—a typical symptom—of these cystic fibrosis patients in the other hotel rooms. Knowing that there are people out there depending on us to work harder and push for better treatments is what drives me. I have no time for politics; my motivation comes from the hope of patients and the desire to get the right drugs to them faster, so they can live longer, do more, and be better.

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Patients first - Parexel employees share how they work with the patients in mind.

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