I contribute to clinical research with expertise and empathy. And I do it
Principal Statistical Programmer
Primary Location: United States, Remote Job ID R0000038030 Category Statistical Programmer Date Posted 02/05/2026Overview
As a member of Parexel’s Statistical Programming group, you analyze, summarize, and graphically present clinical data to assess the safety and efficacy of the clinical trial. It requires attention to detail, a commitment to quality, and effective communication to ensure new treatments reach patients faster. You will work in different therapeutic areas assessing a variety of data entries and endpoints in an ever-changing environment. We provide a fertile environment for growth, with extensive training, mentoring, and technical knowledge sharing.
You will work closely with the client and Parexel teams and collaborate to maximize the collective strength. Experience a supportive and motivating work environment where our teams offer an inherent breadth of knowledge within a diverse and inclusive workplace.
Success Profile
Do you have these soft skills and interpersonal traits to succeed at Parexel?
- Analytical
- Detail-oriented
- Independent
- Proactive
- Responsible
- Team-player
About This Role
Principal Statistical Programmer
Location: Remote
Type: Full-Time
Are you an expert Statistical Programmer looking to lead global studies, shape best practices, and serve as a trusted consultant to sponsors? Join our team as a Principal Statistical Programmer and play a critical role in the analysis and reporting of clinical trial data. In this senior-level position, you will act as a subject matter expert, provide strategic programming leadership, and ensure high-quality, regulatory-compliant deliverables across multiple studies and therapeutic areas. Must have experience supporting Medical Affairs and utilizing R.
Key Accountabilities
🔹 Strategic Leadership & Project Management
- Serve as Statistical Programming Lead on assigned projects.
- Lead programming teams to deliver high‑quality outputs within agreed timelines and budget.
- Drive project planning activities including start-up, resource allocation, and development of global programs and tracking tools.
- Review statistical analysis plans (SAPs), mock shells, and database specifications.
- Partner closely with sponsors, Biostatistics Leads, Data Management, and other stakeholders.
- Monitor scope, resources, productivity, and project financials.
- Support issue resolution and ensure smooth day‑to‑day study execution.
🔹 Statistical Programming & Quality Delivery
- Develop and QC SDTM, ADaM datasets, analysis outputs, tables, listings, and figures.
- Create and QC dataset specifications, study-level documentation, and regulatory submission materials.
- Ensure all programming activities meet corporate quality standards, SOPs, ICH‑GCP, and regulatory requirements.
- Demonstrate consistent first-time quality in deliverables through rigorous QC practices.
🔹 Training, Mentorship & Knowledge Sharing
- Maintain and deepen knowledge of global clinical and regulatory standards.
- Mentor team members and provide project-specific training.
- Lead knowledge-sharing initiatives across the department.
- Expand understanding of internal processes, SAS techniques, and cross-functional workflows.
🔹 Operational Excellence & Compliance
- Maintain study documentation to ensure traceability and regulatory readiness.
- Participate in audits and inspections as needed.
- Contribute to process improvement, technology assessments, and operational optimization.
- Provide expert programming consultancy to sponsors.
- Represent Statistical Programming on cross-functional initiatives and external meetings.
Skills & Competencies
- Advanced SAS programming expertise.
- Strong analytical and problem‑solving skills.
- Deep understanding of clinical programming standards (e.g., CDISC, 21 CFR Part 11).
- Strong project management capabilities with the ability to manage competing priorities.
- Excellent organizational skills and attention to detail.
- Ability to lead and mentor global teams effectively.
- Strong business acumen, financial awareness, and client-focused approach.
- Excellent communication, presentation, negotiation, and influencing skills.
- Ability to adapt and learn new systems in an evolving technical environment.
- Demonstrated commitment to quality and continuous improvement.
Knowledge & Experience
- Proven experience successfully leading teams in a statistical programming environment.
- Strong command of written and spoken English.
- Experience supporting clinical trials across therapeutic areas is highly desirable.
Education
- Bachelor’s degree in a relevant discipline (e.g., Statistics, Computer Science, Mathematics, Life Sciences) or equivalent work experience.
#LI-REMOTE
EEO Disclaimer
Parexel is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to legally protected status, which in the United States includes race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or protected veteran status.
Potential Career Path
Parexel offers career paths for Statistical Programmers to progress in their technical position or managerial position, as well as options to move to other areas of the business.
- Statistical Programmer I
- Statistical Programmer II
- Senior Statistical Programmer
- Subject Matter ExpertPeople Management
Employee Insights
Why Statistical Programmers work at Parexel
